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Within the TME, high CHKA expression in tumor cells transforms them into metabolic choline sinks, depriving nearby immune cells, such as tumor-infiltrating lymphocytes (TILs), of choline needed for their own membrane synthesis, thereby contributing to immunosuppression (Li et al., 2025)

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Contains:10 sterile vials x 238 mg/0.0084 oz.

Cells were then incubated for 24 h with either curcumin or gemcitabine