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Furthermore, the current lack of unified and standardized in vitro and in vivo evaluation models not only limits systematic comparisons of different stimuli-responsive nanoplatforms in terms of drug loading capacity, release kinetics, and biodistribution, but also hinders prospective assessments of their long-term safety and immunogenicity

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is a motivating factor for further investigation, due to the significant potential upside of the development of a medication to reverse cataract grade