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Discussion Our multi-omics study delves into the molecular mechanisms of ASD with a focus on Shank3 Δ 4–22 and Cntnap2 −/− mouse models

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121 Consistent with this, the metal binding affinity for Mg II and noncognate cations are all weak, in the millimolar range, which ensures a Mg II -specific response as this is the only metal in the cell that reaches millimolar bioavailability (Figure 8A)