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Published animal studies using BPC-157, including those extending across multiple weeks of daily administration, have not documented tumor formation or accelerated malignant growth as an observed outcome

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70,71 For example, a small interfering RNA (siRNA) NP targeting macrophage Ca 2+ /calmodulin-dependent protein kinase has been shown to improve all signs of plaque stability in advanced atherosclerosis of Ldlr −/− mice 72 via an increase in expression of MER tyrosine-protein kinase to drive inflammation resolution