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Soon after, we obtained also a set of covalent inhibitors of human LAT1 with the highest affinity so far described (97)

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There are three potential mechanisms through which glyphosate formulations and glyphosate itself could induce neuroexcitotoxicity in the hippocampus: (1) Chelation of manganese: Glyphosate may chelate manganese, rendering it unavailable as a cofactor for glutamine synthetase, an enzyme crucial for glutamate metabolism