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41 Podocyte-specific deletion of Abca1 (Abca1fl/fl) is associated with cardiolipin-driven mitochondrial dysfunction, predisposing mice to DKD

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Therapeutic Interventions : Strategies to modulate the SAM/SAH ratio include the use of SAM-e supplements (to boost SAM levels) or folate and B-vitamin supplementation to promote methionine remethylation, thereby restoring methylation potential

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