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To target certain brain regions for electrical stimulation and regulation during DBS, an electrode is implanted in specific brain regions and high-frequency electrical stimulation (100–200 Hz) is delivered to mimic the effect of a lesion without destroying brain tissue

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Both the in vitro and the “cellular test tube” approach strongly suggest that DsbA does not interact with glutathione itself, indicating that the role of glutathione in the periplasmic redox homeostasis is independent of the known mechanism for disulfide bond formation in E