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This review elucidates how SGLT2 inhibitors promote renal protection in DKD by regulating ferroptosis, supported by both mechanistic insights and clinical evidence

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Although the analyses of endocytosis under in vivo settings in LNs remain technically and methodologically challenging, we find it interesting that the transfer process through the sinus floor has apparent similarities to fast and ultrafast forms of endocytosis, which have so far been identified only in synaptic terminals (56, 58, 59)