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In a randomized trial involving Simmental × Yili brown calves, daily supplementation with 500 mg SBWP significantly increased body weight and average daily gain by approximately 4.9% and 28.5%, respectively, while decreasing the feed-to-gain ratio by nearly 23%

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The molecular pathogenesis of Lynch syndrome follows the classical Knudson two-hit model, in which a germline alteration constitutes the first hit and subsequent somatic inactivation of the remaining wild-type allele results in biallelic MMR deficiency, microsatellite instability (MSI), and tumorigenesis [32,33,34,35,36,37,38,39]