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Similarly, inhibition of peroxisome biogenesis and UGCG-dependent ceramide metabolism with NNC 55-0396 and D,L-threo-PPMP, respectively, induced apoptosis in BRAFi and MEKi persisters 56

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Overexpression of CrOT in HepG2 cells decreases intracellular medium-chain and very long-chain fatty acids, with no effects on long chain fatty acids