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[35] Programmed cell death [edit] Dysregulation of apoptosis (programmed cell death) is believed to play a role in the pathogenesis of a variety of autoimmune diseases, though its role in Sjögren's disease is controversial

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As a member of the sirtuin protein family known for longevity, SIRT6 exhibits various catalytic enzyme activities crucial for processes such as anti-aging, chromatin regulation, transcriptional control, lipid metabolism, and DNA damage repair