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Some of these strategies include restricting heavy metals to the cell wall, vascular sequestration, and synthesis of various biochemical compounds, such as phyto-chelators and organic acids, to bind the free moving heavy metal ions so that the toxic effects are minimized

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However, a recent report by the American Acute Liver Failure Study Group noted that acetaminophen toxicity was responsible for most cases and that the classic forms of HELLP and AFLP account for only a minority of ALF cases [76]