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Discussion of conflicting research and areas requiring future investigations Many chemotherapeutic approaches are designed to elevate intracellular ROS levels to induce irreparable cellular damage, ultimately triggering apoptosis in tumour cells (372)

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FVII activity Factor VII (FVII) activity in the cell medium was determined using the Human FVII Chromogenic Activity Kit (Nordic BioSite AB, Täby, Sweden) according to the manufacturer’s instructions

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