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Some frameworks suggest that the interaction of these peptides could influence intracellular mediators relevant to receptor activation and downstream transcriptional regulators

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Besides, it stimulated expression of early growth response 1 (egr-1) gene responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve growth factor 1-A binding protein-2 (nab2)) (44)