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Studies on steady-state pharmacokinetics and tolerability of 2000 mg trans -resveratrol, administered twice daily with food, quercetin and alcohol (ethanol) showed that trans -resveratrol was well-tolerated by healthy subjects, although diarrhea was frequently observed [149]

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The median duration of treatment was 12 months (range 4–32) and the 1-year survival rate was 73.8%

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