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Fungal-derived cellobiose metabolic pathway fuels T cells to bypass intratumoral glucose competition: Cell

Sung et al.’s investigation into liver Kupffer cells disclosed 298 lactylation sites in 181 proteins, predominantly localized in the nucleus (60%), cytoplasm (28%), mitochondria (4%), cell projections (3%), and chromosomes (3%) [61]

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Unlike apoptosis, necrosis and autophagy, ferroptosis is an iron and ROS-dependent cell death having altered cytological characteristics, including deformed and ruptured outer mitochondrial membrane and reduced mitochondria cristae [61]

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