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Another study in 2019 indicated that NIN reduced α-SMA and Smad3 protein and mRNA levels and blocked oxidative stress, inflammation and the TGF-β-Smad3 and JNK-Smad3 pathways, thereby carrying out its antifibrotic effects (Hernández-Aquino et al., 2019)

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[PMID: 23407943]

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