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ST, Symptomatic therapy - therapies focus on relieving symptoms without directly affecting the disease’s underlying mechanisms, DMT, Disease-modifying therapy - treatments designed to slow down or alter the progression of a disease, DA antagonist, dopamine agonist - a type of drug that activates dopamine receptors in the brain, mimicking the effects of dopamine, GBA, gene encoding the enzyme glucocerebrosidase (GCase) - mutations in GBA are among the most significant genetic risk factors for PD, hESC-DA, human embryonic stem cell-derived dopamine neurons - transplanting hESC-DA neurons into animal models is apparently known to restore dopamine neurotransmission and improve motor function, LD, Levodopa - a key medication used to treat Parkinson’s disease, as it helps replenish dopamine levels in the brain, GLP-1R, Glucagon-like peptide-1 receptor - drugs that mimic the natural GLP-1 hormone, which helps regulate blood sugar levels and appetite
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[DOI] [PMC free article] [PubMed] [Google Scholar] 474.Manik M, Singh RK
