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We proposed at § 512.730(e)(3)(ii)(A) to define “significant changes or errors” regarding instances in which the cost measure score could not be calculated as changes or errors external to the care provided, and that CMS determines may lead to misleading or inaccurate results that negatively impact the measure's ability to reliably assess performance

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What the Clinical-Trial Evidence Shows Survodutide's Phase 3 SYNCHRONIZE-1 trial studied adults with obesity or overweight and an obesity-related complication, without diabetes