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CGA can facilitate cholesterol elimination by modulating homeostasis of bilirubin and bile acids via farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) gamma coactivator 1-alpha (PGC-1α) or fibroblast growth factor (FGF) 15 pathways [42,43]

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The major location, within the brain, for norepinephrine synthesis is the locus coeruleus of the brainstem