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Exercise induces mechanical signals for cytoskeletal and transmembrane-bound proteins, such as integrins, which elicit increased Wnt/β-catenin signaling in the bone, promoting bone formation and suppressing bone resorption

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This conversion can be initiated by plant-derived myrosinase, released upon tissue damage (e.g., chewing), or by microbial myrosinase in the gut (43)

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