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The geometric isomerization of the double bond could, in principle, be determined by the coupling constant of the methylene protons which is larger for the trans ( 3 J ≈ 15 Hz) than that of the cis bonds ( 3 J ≈ 10 Hz)

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These structural protection effects make SS-31 particularly relevant for research into cardiac insufficiency, neurodegenerative disease, and age-related mitochondrial dysfunction

Glutathione is the most abundant intracellular thiol