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Discovery of key mechanism in Huntington's Disease could pave the way for early detection and treatment — Department of Pharmacology

Biochemistry 1990

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When selenium is reduced, some selenoproteins in the body quickly disappear (low grades), while others can continue to be synthesized even when selenium levels are reduced (high grades) ( GPX2 was the first selenoprotein identified as a target of the Wnt pathway, and its promoter contains five β-catenin/TCF binding sites (TBE) (Yu et al., 2021)