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In further embodiments, the invention encompasses a cation of Formula IA, wherein: the cation of Formula IA includes two or more non-hydrogen substituents at positions R 2 -R 8 , and wherein: R 5 is H or NH 2 , R 6 is H or F

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When we don't get enough vitamin B6, it can lead to: Higher homocysteine levels, which are a known risk factor for atherosclerotic cardiovascular disease, have been associated with insulin resistance and Type 2 diabetes