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Ethoxyresorufin O-deethylase and methoxyresorufin O-demethylase activities were measured in the same way as described for the pentoxyresorufin assay, except that the concentration of substrates was 1.7 mM ethoxyresorufin and 5 mM methoxyresorufin assays were carried out using the microsomal fraction of the tissue (Budriesi et al., 2018)

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At 4 d.p.i., tissues were collected, and viral RNA levels tissues were measured (n = 7 and 11, respectively)