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T3 regulation of growth plate chondrocyte proliferation and differentiation in vitro has been shown to involve a number of growth factor signaling pathways including IGF-1, Wnt, the Ihh/PTHrP feedback loop and FGFR3 (Figure 2) (55,82,83)

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The National Transportation Safety Board (NTSB) recommended Tuesday that states lower the legal blood alcohol concentration (BAC) level while driving from 0.08 to 0.05 or lower