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[DOI] [PubMed] [Google Scholar] Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C

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revealed that administration of resveratrol (800 mg/day) as a natural supplement in PCOS patients who were candidates for IVF for 40 days can reform the molecular pathways related to angiogenesis in granulosa cells through down-regulation of VEGF and hypoxia-inducible factor 1 ( HIF-1 ), as a key factor for modulation of VEGF and other angiogenic factors