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These ectoenzymes, expressed by resident cells (43, 44), sustain the CD38/CD203a/CD73 pathway ( Figure 1 ), which sequentially generates ADPR, AMP, and ultimately immunosuppressive ADO (45), thereby linking purinergic metabolism to immune evasion (44, 46, 47)

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When you're injecting something into your body, these differences aren't trivial, they're potentially dangerous