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A deficiency of NAD+ may disrupt the circadian rhythm and result in effects such as daytime sleepiness, restless sleep, hormonal imbalances, and mood alterations, among others

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The relative abundance of saturated, monounsaturated (MUFA), and polyunsaturated (PUFA) fatty acids within membrane PC determines fluidity, lipid raft integrity, and receptor clustering, all of which are critical for vascular tone and nitric oxide (NO) signaling (Yaghmour et al., 2025)