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“It also opens the door for the idea that for TNF-inhibitor users, perhaps other live virus vaccine also may be safe and might be considered in certain circumstances.” The researchers are now planning a trial to study the safety and effectiveness of the newer non-live-virus shingles vaccine, Shingrex, in patients with arthritis and inflammatory bowel disease who were excluded from the clinical trials leading to its approval

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When B12 is low, these processes start to slow down, which is why the symptoms tend to show up across so many different systems at once