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CoQ10 can be synthesized by the mevalonate (MVA) pathway using acetyl coenzyme A (66)

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Similarly, this compound inhibits Th17 and Th1 cell differentiation by reducing STAT3 and STAT4 phosphorylation, respectively, and suppresses mTORC1 pathway activity independently of PI3K/AKT and ERK signaling in DSS-induced colitis mice [495]