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A similar pharmacological profile is exhibited by astragaloside IV, which has been reported to restore myocardial contractility, enhance blood and oxygen supply to the heart, stimulate angiogenesis, maintain normal mitochondrial function and energy balance in cardiomyocytes

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Mitochondria possess multiple enzymes for degrading ETC-derived ROS, the most prevalent and best characterised being mitochondrial superoxide dismutase (MnSOD/SOD2) [86]