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LO2 cells and HepG2 cells were respectively divided into five groups in triplicate: control, model, PGPIPN 1, 2 and 3, and seeded respectively into 100 ml cell culture flasks containing 0.5% vol (LO2) or 0.6% vol (HepG2) alcohol, except for control group

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If you have chronic kidney disease or declining renal function, your doctor will monitor your kidney markers through blood tests and may adjust metformin dosing accordingly