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For scars with a persistent red or pink vascular component, pulsed dye laser targets the hemoglobin in the abnormal blood vessels feeding the scar, reducing redness and improving overall appearance

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Moreover, the activity of γ-glutamylcysteine synthetase (γ-ECS), which catalyses the first step of the committed GSH synthesis pathway, is regulated by oxidation, both at the level of oxidant-induced de-repression of γ-ECS translation and at the post-translational level by oxidation of enzyme thiol groups (Hicks et al ., 2007

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