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Microglial nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), mitochondria, and changes in iron levels are three of the most common sources of ROS

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Evodiamine treatment markedly reduces MMP‐2 mRNA and protein levels, potentially through reduced translocation of nuclear factor‐κB p65, but does not affect MMP‐9 expression levels [106]