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PLASMA DRUG CONCENTRATIONS AS THERAPEUTIC GUIDELINES Most pharmacokinetic information is derived from plasma drug concentrations, even though pharmacologic action depends on drug concentration at a particular effector site, which is often a specific drug receptor

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Una aplicación clásica de isótopos estables la constituye el empleo de 13 C-aminopirina para distinguir diferentes grados de enfermedad hepática que afectan los procesos de demetilación en el citocromo P-450