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[DOI] [PMC free article] [PubMed] [Google Scholar] 235.Haase S., Haghikia A., Wilck N., Müller D.N., Linker R.A

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As a consequence, FXN deficiency leads to a pronounced oxidative stress [17,18] since ISCs constitute prosthetic groups of essential proteins like respiratory chain complexes and energy metabolism enzymes like aconitase [19]