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By blocking the activation of the transcription factor NF-κB, melatonin limits the transcription of genes encoding cytokines, chemokines, and pro-inflammatory enzymes (e.g., cyclooxygenase-2 (COX-2), iNOS) [157,158]

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Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence