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Cardiovascular Research A growing body of preclinical work (Sikiric et al., Biomedicines 2022) has investigated BPC-157 in cardiovascular models including myocardial infarction, heart failure, pulmonary hypertension, arrhythmias, and thrombosis — with proposed mechanisms involving NO pathway modulation and angiogenic signaling restoration

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Building upon this foundation, we further evaluate novel therapeutic strategies targeting this network, particularly the feasibility of enhancing treatment efficacy through combined blockade of hormonal signaling and oxidative damage