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As an example, in its letter to FirstCham Co., Ltd., the FDA stated the firm “failed to adequately design [its] water system to ensure it was suitable for producing water used in the formulation of [its] drug products (i.e., multiple dead-legs, non-circulating loop) and to provide documentation of its qualification

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A one-way analysis of variance (ANOVA) with Dunnett's posthoc test was used to compare multiple groups (different inhibitor treatments or concentration effects in cellular assessments) to controls