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Liver Disease A quantitative mass spectrometry analysis of healthy controls and patients with nonalcoholic steatohepatitis (NASH) revealed that, consistent with other metabolic diseases, circulating levels of l-serine are significantly reduced in such patients (9, 19)

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Moreover, through signaling regulation of lipid metabolism involving Retinoid X receptors alpha (RXRsα), the liver could be protected by RA