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Alternatively, inside the cell, GAPDH in the form of aggregates can promote Aβ40 amyloidogenesis and form stable complexes that interact with the mitochondria causing disruption of the mitochondrial membrane potential and release of cytochrome c into the cytosol, leading ultimately to cell death [313] (figure 2)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Maecker HT, Wang W, Rosenberg-Hasson Y, Semelka RC, Hickey J, Koran LM

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