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There are marked circadian variations in the metabolism of 5-fluorouracil related to 24-h cyclic fluctuations in Dihydrouracil Dehydrogenase activity, which are reflected in inverse variations of 5-fluorouracil blood concentrations during infusions

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doi: 10.3390/cells9061505 147 SunYVashishtAATchieuJWohlschlegelJADreierL

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