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This process led to a significant promotion of CF proliferation (increased rate) and transdifferentiation of the CFs into myofibroblasts (upregulation of α-SMA expression) through activation of the Hippo/YAP signaling pathway

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stated that drug site I contain a binding area for warfarin–azapropazone, which contains two overlapping binding sites for azapropazone and warfarin (Fehske et al., 1980, 1981, 1982)

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