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For example, copper provides the catalytic activity for the antioxidant enzyme copper-zinc superoxide dismutase (CuZnSOD), while zinc plays a critical structural role

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Similarly, in studies of AC2, the Lgr5-binding octapeptide, Sh-Polypeptide 9, and AcSDKP, which promote the proliferation of various cell types, including DPCs, HFSCs, and matrix cells, do not demonstrate therapeutic effects in vivo [95,99,110,113]

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