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Increased transcription of IL-6 and IL-1β, mediated through the ERK and the p38 MAPK signal pathways, occurs due to the combined effects of DON and PCV2, although similar effects may be exerted by PCV2 through the JNK signal pathway (115)

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Therefore, striatal tissue from some Gsto2 -shRNA-injected mutants, controls and mutants injected with scrambled shRNA at 3 months were analysed at 15 weeks