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Treatment of idiopathic facial paralysis (Bell's Palsy) and secondary facial paralysis with extracellular vesicles: a pilot safety study | BMC Neurology | Springer Nature Link

While the biological plausibility exists, the evidence does not meet the standard we would require to confirm anti-aging effects

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Furthermore, methodologically, the sinus ligated to the bone provides the absolute obstruction of the sinus while skull bone overlying the sinus eliminates the risk of sinus tear