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The insertion of activated Bax in the outer mitochondrial membrane by caspase-8 produced tBid, the interaction of Bax/ TOM, the oligomerization and induction of pore formation and subsequent release of pro-apoptotic proteins into the cytosol were documented in isolated mitochondria from different Saccharomices cerevisiae yeast mutants [157], consistent with the expected sequence of events in the initiation of apoptosis

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PSM also enables the construction of MOF-on-MOF heterostructures, allowing complementary integration of framework properties