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Dietary and nutritional supplements can in some cases replace drugs, but with the exception of ketogenic diets, there are no officially recommended dietary considerations for patients with epilepsy

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145 – 148 Relevantly, inhibition of complex I has been shown to activate 5′-AMP-activated protein kinase and improves glucose metabolism in diabetes, 149 – 152 supporting the observation that complex I ROS production plays a role in diabetes