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Moreover, both a Fab fragment antibody (Fab 7881) specific for the ghrelin receptor and an antagonist, Compound 21, were added to bRIL-conjugated truncated ghrelin receptor to increase thermostability (Supplementary Fig

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54 More support for this connection comes from a clinical trial in which 69 menopausal women, 32 of whom had fibromyalgia, experienced improvements in sleep, quality of life, and fibromyalgia symptoms after 12 weeks of hormone therapy using bioidentical transdermal estrogen and oral progesterone